Due clinical diligence is required in the investigation of these patients. Conclusion: Transient global amnesia is an interesting syndrome of reversible anterograde amnesia associated with repetitive questioning that occurs with an unclear etiology in middle-aged and elderly individuals. Her memory improved and reverted to normal baseline over the course of a 24-hour hospital stay. Neurologic investigations did not reveal any pathologic findings. Neurologic examination disclosed repetitive questioning with preserved orientation and no focal motor, speech, sensory, coordination, or cranial nerve deficits. Case Presentation: A middle-aged Caucasian woman presented for neurologic evaluation for acute forgetfulness. Although the etiology is unknown, the prognosis usually benign, and no particular treatment is required, it is important for all involved clinicians to recognize the diagnosis and possess knowledge about the evaluation of these affected patients. This review provides a detailed framework for distinguishing transient global amnesia from its dangerous mimics and managing its course in the emergency department.ĭirectory of Open Access Journals (Sweden)įull Text Available Introduction: Transient global amnesia is a syndrome of temporary and reversible disruption of short-term memory accompanied by repetitive questioning. In witnessed transient global amnesia with classic features, a minimalist approach is reasonable, avoiding overtesting, inappropriate medication, and medical interventions in favor of observation, ensuring patient safety, and reassuring patients and their families. Transient global amnesia confers no known long-term risks however, when abnormal signs or symptoms are present, they take precedence and guide the formulation of a differential diagnosis and investigation. The diagnosis is dependent on eliminating other more serious etiologies including toxic ingestions, acute strokes, complex partial seizures, and central nervous system infections. Transient global amnesia is a clinically distinct syndrome characterized by the acute inability to form new memories. įaust, Jeremy Samuel Nemes, Andreea Zaurova, Milana Transient global amnesia: emergency department evaluation and management.
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